Hepatotoxicity and oxidative stress induced by Naja haje crude venom
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چکیده
منابع مشابه
Histological and Ultrastructural Alterations in the Renal Cortex of Rats Induced by the Egyptian Cobra (naja Haje) Crude Venom
In the present study, the histopathological and Ultrastructural changes occurring in the renal cortical cells of rats following intramuscular injection of 1⁄8 LD50 (0.0625 mg/kg body weight) of cobra (Naja haje) crude venom were investigated with the light and transmission electron microscopes. Tissues were obtained for investigation at 4 h, 8 h and 12 h time intervals following injection of th...
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This investigation was performed in order to assess the inflammatory response induced by Naja haje arabica venom (NhaV) in rat hind paw. The inflammatory response was estimated by measuring the edema with a Plethysmometer. The venom (0.625-10μg/paw) produced a dose and timedependent increase in non-hemorrhagic paw edema. The response to NhaV was maximal within 15 min and disappeared in 24 h. Fi...
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BACKGROUND Naja naja atra venom (NNAV) displays diverse pharmacological actions including analgesia, anti-inflammation and immune regulation.In this study, we investigated the effects of NNAV on pulmonary fibrosis and its mechanisms of action. METHODS To determine if Naja naja atra venom (NNAV) can produce beneficial effects on pulmonary fibrosis, two marine models of pulmonary fibrosis were ...
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ژورنال
عنوان ژورنال: Journal of Venomous Animals and Toxins including Tropical Diseases
سال: 2014
ISSN: 1678-9199
DOI: 10.1186/1678-9199-20-42